Adult Cognitive Disease

APOE Amyloid & Tau core 3,381 477 docs

Matched on apoe[234]? apo[- ]?E[234]? apolipoprotein E

Often named withAPP PSEN1 TREM2 V-ATPase (ATP6V)BACE1 LRP8 (ApoER2)

RELN Reelin, synapse & ECM–PNN 2,127 49 docs

Matched on RELN reelin

Often named withAPOE LRP8 (ApoER2)APP PSEN1 DAB1 VLDLR

APP Amyloid & Tau core 1,243 192 docs

Matched on amyloid precursor protein APP

Often named withAPOE PSEN1 BACE1 TREM2 V-ATPase (ATP6V)PVALB (parvalbumin)

TREM2 GWAS / LOAD risk 827 89 docs

Matched on s?TREM2

Often named withAPOE APP PSEN1 NLRP3 PVALB (parvalbumin)C1QA

NLRP3 Microglia & innate immunity 594 65 docs

Matched on NLRP3

Often named withAPOE APP TREM2 PSEN1 PVALB (parvalbumin)MTOR

SST (somatostatin) Neuromodulator / circadian / kynurenine 586 25 docs

Matched on SST somatostatin

Often named withPVALB (parvalbumin)ACAN (aggrecan)APOE APP PSEN1 MMP9

V-ATPase (ATP6V) Autophagy / lysosome / clearance 577 75 docs

Matched on V-ATPase ATP6V vacuolar[- ]?(?:type )?ATPase

Often named withAPOE APP PSEN1 MTOR TFEB TREM2

LILRB2 GWAS / LOAD risk 563 31 docs

Matched on LILRB2 PirB

Often named withC4 (complement)APOE C1QA APP TREM2 MMP9

PSEN1 Amyloid & Tau core 563 138 docs

Matched on PSEN1 PS1 presenilin[- ]?1

Often named withAPP APOE TREM2 MTOR NLRP3 V-ATPase (ATP6V)

PVALB (parvalbumin) Reelin, synapse & ECM–PNN 561 70 docs

Matched on PVALB parvalbumin

Often named withAPOE ACAN (aggrecan)APP MMP9 PSEN1 TREM2

LRP8 (ApoER2) Reelin, synapse & ECM–PNN 525 54 docs

Matched on LRP8 ApoER2 APOER2

Often named withAPOE RELN APP DAB1 PSEN1 VLDLR

MMP9 Reelin, synapse & ECM–PNN 477 55 docs

Matched on MMP-?9

Often named withAPOE PVALB (parvalbumin)ACAN (aggrecan)APP MMP2 PSEN1

CD38 Bioenergetic / mito / NAD 435 29 docs

Matched on CD38

Often named withAPOE PARP1 PVALB (parvalbumin)APP TREM2 MMP2

DAB1 Reelin, synapse & ECM–PNN 424 35 docs

Matched on DAB1 Disabled-1

Often named withLRP8 (ApoER2)APOE RELN APP VLDLR PSEN1

CAMP (LL-37) Microglia & innate immunity 414 20 docs

Matched on LL-?37 cathelicidin

Often named withAPOE V-ATPase (ATP6V)APP NLRP3 TREM2 MMP9

LRP1 Reelin, synapse & ECM–PNN 410 31 docs

Matched on LRP1

Often named withAPOE APP PSEN1 MMP9 PVALB (parvalbumin)TREM2

ARHGEF15 (Ephexin5) Reelin, synapse & ECM–PNN 405 12 docs

Matched on Ephexin-?5 ARHGEF15

Often named withRHOA APOE APP C4 (complement)LILRB2 DAB1

BDNF Trophic / exercise / resilience 322 28 docs

Matched on BDNF

Often named withAPP APOE PSEN1 NTRK2 (TrkB)MTOR AKT1 (Akt)

ACAN (aggrecan) Reelin, synapse & ECM–PNN 307 57 docs

Matched on ACAN aggrecan

Often named withAPOE PVALB (parvalbumin)MMP9 APP PSEN1 TNR (tenascin-R)

C4 (complement) Microglia & innate immunity 298 33 docs

Matched on C4d C4b

Often named withLILRB2 APOE C1QA C3 PVALB (parvalbumin)TREM2

SORL1 GWAS / LOAD risk 288 41 docs

Matched on SORL1 SORLA

Often named withAPOE APP PSEN1 C1QA V-ATPase (ATP6V)C3

PARP1 Bioenergetic / mito / NAD 262 30 docs

Matched on PARP-?1 PARP1

Often named withAPOE PVALB (parvalbumin)APP MMP9 C1QA C3

MTOR Autophagy / lysosome / clearance 258 49 docs

Matched on mTOR MTOR mTORC1 mTORC2

Often named withAPP PSEN1 APOE TREM2 NLRP3 PIK3CA (PI3K)

TARDBP (TDP-43) Neurodegeneration overlap 253 50 docs

Matched on TARDBP TDP-?43

Often named withAPP APOE PSEN1 MTOR V-ATPase (ATP6V)SOD1

HSD17B10 Bioenergetic / mito / NAD 244 4 docs

Matched on HSD17B10 HSD10 ABAD 17β-HSD10 17beta-HSD10

Often named withAPP CYCS (cytochrome c)APOE PINK1 PPIF (cyclophilin D)TIMM23

GPX4 Oxidative stress & ferroptosis 232 19 docs

Matched on GPX4

Often named withAPP PSEN1 APOE PARP1 LRP8 (ApoER2)MTOR

CAV1 (caveolin-1) Vascular / BBB 216 12 docs

Matched on CAV1 caveolin-?1

Often named withAPOE APP PSEN1 GRIN2A GRIN2B LRP1

VCAM1 Vascular / BBB 197 8 docs

Matched on VCAM-?1

Often named withNFKB1 (NF-κB)PARP1 TNF APOE APP IL6

IDO1 Neuromodulator / circadian / kynurenine 175 10 docs

Matched on IDO1 IDO

Often named withAPOE APP IL6 KMO PSEN1 TNF

BACE1 Amyloid & Tau core 173 61 docs

Matched on BACE1

Often named withAPOE APP PSEN1 TREM2 V-ATPase (ATP6V)GSK3B

TNF Microglia & innate immunity 169 50 docs

Matched on TNF

Often named withAPOE APP TREM2 PSEN1 IL6 NLRP3

C1QA Microglia & innate immunity 167 50 docs

Matched on C1q C1QA C1QB

Often named withAPOE C3 CR3 APP TREM2 C4 (complement)

RHOA Reelin, synapse & ECM–PNN 158 20 docs

Matched on RhoA RHOA

Often named withAPOE APP ARHGEF15 (Ephexin5)C4 (complement)DAB1 LILRB2

NFKB1 (NF-κB) Kinase & growth-factor signalling 149 42 docs

Matched on NFKB1 NF-?κB NF-?kB NF-?kappaB

Often named withAPOE APP NLRP3 PSEN1 MMP9 PVALB (parvalbumin)

TOMM40 Bioenergetic / mito / NAD 145 18 docs

Matched on TOMM40

Often named withAPOE APP TOM40 V-ATPase (ATP6V)PINK1 TARDBP (TDP-43)

GSK3B Amyloid & Tau core 144 49 docs

Matched on GSK3B GSK-?3β GSK-?3beta GSK-?3

Often named withAPOE APP PSEN1 LRP8 (ApoER2)DAB1 BACE1

TFEB Autophagy / lysosome / clearance 144 32 docs

Matched on TFEB

Often named withAPP PSEN1 V-ATPase (ATP6V)APOE MTOR MAP1LC3B (LC3)

LRRK2 Neurodegeneration overlap 138 14 docs

Matched on LRRK2

Often named withAPP APOE PSEN1 MTOR TARDBP (TDP-43)GBA

MAOA/MAOB Neuromodulator / circadian / kynurenine 137 12 docs

Matched on MAO-A MAO-B MAOA MAOB monoamine oxidase

Often named withAPOE APP PSEN1 ACAN (aggrecan)ATF4 BDNF

SQSTM1 (p62) Autophagy / lysosome / clearance 136 24 docs

Matched on SQSTM1 p62

Often named withAPP MTOR PSEN1 MAP1LC3B (LC3)APOE TFEB

PINK1 Bioenergetic / mito / NAD 135 25 docs

Matched on PINK1

Often named withPRKN APP MTOR APOE PSEN1 NLRP3

PRNP Neurodegeneration overlap 133 23 docs

Matched on PRNP prion protein PrP

Often named withAPOE APP PSEN1 TARDBP (TDP-43)LRP1 C4 (complement)

PRKN Bioenergetic / mito / NAD 131 24 docs

Matched on PRKN parkin PARK2

Often named withPINK1 APP MTOR PSEN1 APOE NLRP3

PYCARD Microglia & innate immunity 127 15 docs

Matched on PYCARD ASC

Often named withNLRP3 CASP1 APP PSEN1 IL18 NFKB1 (NF-κB)

MAP1LC3B (LC3) Autophagy / lysosome / clearance 121 24 docs

Matched on MAP1LC3B LC3

Often named withAPP PSEN1 MTOR SQSTM1 (p62)V-ATPase (ATP6V)APOE

GFAP Astrocyte & glial markers 117 24 docs

Matched on GFAP

Often named withAPOE TREM2 PSEN1 ACAN (aggrecan)APP P2RY12

C3 Microglia & innate immunity 116 44 docs

Matched on C3

Often named withC1QA APOE CR3 TREM2 APP C4 (complement)

GRN (progranulin) Autophagy / lysosome / clearance 115 11 docs

Matched on progranulin GRN

Often named withPSEN1 APP MTOR GBA V-ATPase (ATP6V)APOE

VLDLR Reelin, synapse & ECM–PNN 110 29 docs

Matched on VLDLR

Often named withAPOE DAB1 LRP8 (ApoER2)RELN APP PSEN1

FYN Amyloid & Tau core 105 19 docs

Matched on Fyn FYN

Often named withAPP APOE PSEN1 AKT1 (Akt)PIK3CA (PI3K)PRNP

MME (neprilysin) Amyloid & Tau core 102 22 docs

Matched on MME neprilysin

Often named withAPOE APP BACE1 PSEN1 TREM2 SST (somatostatin)

AKT1 (Akt) Kinase & growth-factor signalling 93 45 docs

Matched on AKT1 Akt

Often named withAPOE APP PIK3CA (PI3K)PSEN1 MTOR TREM2

PP2A Amyloid & Tau core 91 18 docs

Matched on PP2A PPP2CA

Often named withAPOE APP PSEN1 GSK3B NLRP3 RELN

CASP1 Microglia & innate immunity 90 19 docs

Matched on CASP1 caspase[- ]?1

Often named withNLRP3 APP PSEN1 TREM2 APOE NFKB1 (NF-κB)

MMP2 Reelin, synapse & ECM–PNN 89 32 docs

Matched on MMP-?2

Often named withMMP9 APOE PVALB (parvalbumin)ACAN (aggrecan)TREM2 ADAMTS4

TOM40 Bioenergetic / mito / NAD 88 9 docs

Matched on TOM40

Often named withAPOE APP PINK1 PRKN TOMM20 NLRP3

C9ORF72 Neurodegeneration overlap 87 9 docs

Matched on C9ORF72

Often named withTARDBP (TDP-43)APP HTT (huntingtin)APOE GBA MAP1LC3B (LC3)

EPHB2 Reelin, synapse & ECM–PNN 86 8 docs

Matched on EphB2 EPHB2

Often named withAPP ARHGEF15 (Ephexin5)C4 (complement)LILRB2 RHOA APOE

SNCA Neurodegeneration overlap 86 23 docs

Matched on SNCA α-synuclein alpha-synuclein α-syn

Often named withAPOE APP TARDBP (TDP-43)PSEN1 SOD1 TREM2

CR3 Microglia & innate immunity 84 33 docs

Matched on CR3 CD11b ITGAM

Often named withC1QA APOE C3 TREM2 APP C4 (complement)

BCAN (brevican) Reelin, synapse & ECM–PNN 81 27 docs

Matched on BCAN brevican

Often named withACAN (aggrecan)MMP9 APOE PVALB (parvalbumin)APP NCAN (neurocan)

GBA Neurodegeneration overlap 81 13 docs

Matched on GBA1 GBA

Often named withAPP MTOR PSEN1 V-ATPase (ATP6V)APOE TARDBP (TDP-43)

NGF Trophic / exercise / resilience 81 16 docs

Matched on nerve growth factor NGF

Often named withAPOE APP BDNF PSEN1 BACE1 NTRK1 (TrkA)

NEFL (NfL) Reelin, synapse & ECM–PNN 80 16 docs

Matched on NEFL neurofilament light NfL

Often named withAPOE APP PSEN1 TARDBP (TDP-43)TREM2 MTOR

BIN1 GWAS / LOAD risk 76 23 docs

Matched on BIN1

Often named withAPOE APP PSEN1 SORL1 TREM2 PICALM

NTRK2 (TrkB) Trophic / exercise / resilience 76 15 docs

Matched on NTRK2 TrkB

Often named withBDNF APP APOE PSEN1 AKT1 (Akt)GRIN2B

TNR (tenascin-R) Reelin, synapse & ECM–PNN 76 31 docs

Matched on tenascin-?R TNR

Often named withACAN (aggrecan)PVALB (parvalbumin)MMP9 APOE TREM2 APP

SOD1 Oxidative stress & ferroptosis 74 19 docs

Matched on SOD1

Often named withAPP APOE TARDBP (TDP-43)PSEN1 HTT (huntingtin)TREM2

HIF1A Bioenergetic / mito / NAD 73 4 docs

Matched on HIF1A HIF-?1

Often named withAPP MTOR TARDBP (TDP-43)IL1B PSEN1 TFEB

CDC42 Reelin, synapse & ECM–PNN 72 7 docs

Matched on CDC42

Often named withAPOE APP ARHGEF15 (Ephexin5)RHOA C4 (complement)EPHB2

CD33 GWAS / LOAD risk 70 19 docs

Matched on CD33

Often named withTREM2 APOE APP PSEN1 C1QA CX3CR1

HTT (huntingtin) Neurodegeneration overlap 70 14 docs

Matched on HTT huntingtin

Often named withTARDBP (TDP-43)APP APOE PSEN1 SOD1 MTOR

BECN1 Autophagy / lysosome / clearance 69 17 docs

Matched on BECN1 Beclin

Often named withAPOE APP MTOR PSEN1 TFEB V-ATPase (ATP6V)

P2RY12 Microglia & innate immunity 69 33 docs

Matched on P2RY12 P2Y12

Often named withAPOE TREM2 TMEM119 PVALB (parvalbumin)ACAN (aggrecan)CX3CR1

SIRT1 Bioenergetic / mito / NAD 69 23 docs

Matched on SIRT1

Often named withAPP APOE BACE1 PARP1 PSEN1 PVALB (parvalbumin)

AQP4 Vascular / BBB 67 6 docs

Matched on AQP4

Often named withAPOE APP CLDN5 IL6 LRP1 PARP1

PIK3CA (PI3K) Kinase & growth-factor signalling 65 39 docs

Matched on PIK3CA PI3-?kinase PI3K

Often named withAKT1 (Akt)APOE APP MTOR PSEN1 TREM2

RAB5A Autophagy / lysosome / clearance 65 11 docs

Matched on RAB5A Rab5

Often named withAPP APOE PSEN1 BACE1 V-ATPase (ATP6V)SORL1

NFE2L2 (NRF2) Oxidative stress & ferroptosis 63 12 docs

Matched on NFE2L2 NRF2

Often named withAPP MTOR PSEN1 GPX4 APOE PRKAA (AMPK)

AIFM2 (FSP1) Oxidative stress & ferroptosis 62 4 docs

Matched on FSP1 AIFM2

Often named withALOX15 APOE GPX4 NFE2L2 (NRF2)SLC7A11 (xCT)ACSL4

FTH1/FTL (ferritin) Oxidative stress & ferroptosis 62 17 docs

Matched on ferritin FTH1 FTL

Often named withAPOE NLRP3 TREM2 APP C1QA C3

PLCG2 GWAS / LOAD risk 62 14 docs

Matched on PLCG2

Often named withTREM2 ABI3 APOE CD33 C3 MS4A

PRKAA (AMPK) Bioenergetic / mito / NAD 62 20 docs

Matched on AMPK PRKAA1 PRKAA2

Often named withAPP MTOR PSEN1 SQSTM1 (p62)NLRP3 TFEB

CLDN5 Vascular / BBB 60 6 docs

Matched on CLDN5 claudin-?5

Often named withAPOE IL6 TNF ABCB1 (P-gp)APP AQP4

GSDMD Microglia & innate immunity 59 9 docs

Matched on GSDMD gasdermin

Often named withNLRP3 APP CASP1 PSEN1 PYCARD NFKB1 (NF-κB)

KMO Neuromodulator / circadian / kynurenine 59 6 docs

Matched on KMO

Often named withAPOE IDO1 TREM2 ACAN (aggrecan)APP IDO2

CX3CR1 Microglia & innate immunity 58 25 docs

Matched on CX3CR1

Often named withP2RY12 TREM2 APOE PVALB (parvalbumin)ACAN (aggrecan)TMEM119

MAPK14 (p38) Kinase & growth-factor signalling 58 8 docs

Matched on MAPK14 p38

Often named withAPP PSEN1 APOE TREM2 MTOR C1QA

PSEN2 Amyloid & Tau core 56 29 docs

Matched on PSEN2 PS2 presenilin[- ]?2

Often named withAPP PSEN1 APOE TARDBP (TDP-43)TREM2 BACE1

IL6 Microglia & innate immunity 55 24 docs

Matched on IL-?6

Often named withTNF TREM2 APOE APP MTOR NLRP3

FNDC5 (irisin) Trophic / exercise / resilience 53 3 docs

Matched on FNDC5 irisin

Often named withAPOE ACAN (aggrecan)BDNF DCX (doublecortin)GFAP PSEN1

ADAMTS4 Reelin, synapse & ECM–PNN 52 24 docs

Matched on ADAMTS-?4

Often named withPVALB (parvalbumin)MMP9 ACAN (aggrecan)APOE MMP2 TREM2

CTSB Autophagy / lysosome / clearance 52 15 docs

Matched on CTSB cathepsin B

Often named withAPOE NLRP3 APP PSEN1 CTSD ACAN (aggrecan)

TTR (transthyretin) Amyloid & Tau core 52 2 docs

Matched on TTR transthyretin

Often named withAPOE CLU ABI3 APP C3 CLDN5

NRGN (neurogranin) Reelin, synapse & ECM–PNN 51 4 docs

Matched on NRGN neurogranin

Often named withAKT1 (Akt)APOE GFAP NEFL (NfL)PIK3CA (PI3K)PSEN1

CSF1R Microglia & innate immunity 50 17 docs

Matched on CSF1R

Often named withPVALB (parvalbumin)APOE MMP9 TREM2 ACAN (aggrecan)MMP2

SARM1 Bioenergetic / mito / NAD 50 8 docs

Matched on SARM1

Often named withPARP1 PVALB (parvalbumin)APP GPX4 PSEN1 ADAMTS4

ADAM10 Amyloid & Tau core 47 16 docs

Matched on ADAM10

Often named withAPOE APP BACE1 PSEN1 SIRT1 TREM2

DLG4 (PSD-95) Reelin, synapse & ECM–PNN 47 20 docs

Matched on DLG4 PSD-?95

Often named withAPP APOE PSEN1 DAB1 LRP8 (ApoER2)PIK3CA (PI3K)

SV2A Reelin, synapse & ECM–PNN 47 10 docs

Matched on SV2A

Often named withAPOE APP C1QA C3 C4 (complement)CR3

TIMP3 Reelin, synapse & ECM–PNN 47 6 docs

Matched on TIMP-?3

Often named withACAN (aggrecan)APP BCAN (brevican)MMP9 PSEN1 PVALB (parvalbumin)

ACAT1 Lipid, sterol & membrane 45 11 docs

Matched on ACAT1

Often named withAPOE APP PSEN1 ABCA1 SOAT1 V-ATPase (ATP6V)

TREX1 Vascular / BBB 45 2 docs

Matched on TREX1

Often named withAPOE APP CGAS MEF2C PSEN1 SLC18A2 (VMAT2)

ACHE Neuromodulator / circadian / kynurenine 44 16 docs

Matched on ACHE acetylcholinesterase AChE

Often named withCHRNA7 APOE CHAT (ChAT)NGF NTRK1 (TrkA)PARP1

NAMPT Bioenergetic / mito / NAD 44 8 docs

Matched on NAMPT

Often named withPARP1 APOE CD38 APP ATF4 NMRK1

ATP synthase (ATP5x) Bioenergetic / mito / NAD 43 5 docs

Matched on ATP5A1 ATP synthase OSCP ATP5PO

Often named withAPP PSEN1 CD38 MTOR PRKAA (AMPK)APOE

CTSD Autophagy / lysosome / clearance 43 18 docs

Matched on CTSD cathepsin D

Often named withAPP PSEN1 APOE MAP1LC3B (LC3)MTOR V-ATPase (ATP6V)

SPI1 GWAS / LOAD risk 43 8 docs

Matched on SPI1 PU\.1

Often named withPSEN1 TREM2 APOE APP MTOR NLRP3

TMEM119 Microglia & innate immunity 42 25 docs

Matched on TMEM119

Often named withP2RY12 APOE CX3CR1 PVALB (parvalbumin)SALL1 ACAN (aggrecan)

OPTN Neurodegeneration overlap 41 9 docs

Matched on OPTN optineurin

Often named withAPP MTOR PINK1 PRKN PSEN1 SQSTM1 (p62)

MAPT Amyloid & Tau core 40 9 docs

Matched on MAPT

Often named withAPOE APP TARDBP (TDP-43)CR3 LRP1 MTOR

HTRA1 Vascular / BBB 39 1 doc

Matched on HTRA1

Often named withABCA1 ABCA7 ABCB1 (P-gp)ABCG2 (BCRP)ABI3 ACAN (aggrecan)

NOTCH3 Vascular / BBB 38 1 doc

Matched on NOTCH3

Often named withABCA1 ABCA7 ABCB1 (P-gp)ABCG2 (BCRP)ABI3 ACAN (aggrecan)

ATF4 Cell death & ER stress 37 10 docs

Matched on ATF4

Often named withAPOE PARP1 CD38 APP MTOR NAMPT

SDC (syndecan) Reelin, synapse & ECM–PNN 37 6 docs

Matched on SDC1 SDC2 SDC3 SDC4 syndecan

Often named withAPOE APP PSEN1 RELN ACAN (aggrecan)DAB1

TYROBP GWAS / LOAD risk 37 16 docs

Matched on TYROBP DAP12

Often named withTREM2 APOE ACAN (aggrecan)MTOR P2RY12 PVALB (parvalbumin)

CDKN1A (p21) Epigenetic & senescence 36 9 docs

Matched on CDKN1A p21

Often named withAPOE APP NLRP3 AKT1 (Akt)C4 (complement)MTOR

HDAC2 Epigenetic & senescence 36 3 docs

Matched on HDAC2

Often named withAPOE SIRT1 ACAN (aggrecan)APP BACE1 BCAN (brevican)

SNAP25 Reelin, synapse & ECM–PNN 36 6 docs

Matched on SNAP-?25

Often named withAPOE SNCA GFAP NEFL (NfL)NRGN (neurogranin)PIK3CA (PI3K)

UBE3A Autophagy / lysosome / clearance 36 6 docs

Matched on UBE3A

Often named withAPP ARHGEF15 (Ephexin5)EPHB2 RHOA APOE C4 (complement)

ULK1 Autophagy / lysosome / clearance 36 11 docs

Matched on ULK1

Often named withMTOR APP SQSTM1 (p62)MAP1LC3B (LC3)NLRP3 PRKAA (AMPK)

VPS35 Autophagy / lysosome / clearance 36 7 docs

Matched on VPS35

Often named withAPOE APP PSEN1 SORL1 BACE1 TREM2

BACE2 Amyloid & Tau core 35 4 docs

Matched on BACE2

Often named withAGER (RAGE)APOE MMP9 PARP1 PVALB (parvalbumin)ABCB1 (P-gp)

CX3CL1 (fractalkine) Microglia & innate immunity 35 13 docs

Matched on CX3CL1 fractalkine

Often named withCX3CR1 APOE P2RY12 TREM2 APP ACAN (aggrecan)

EIF2S1 (eIF2α) Cell death & ER stress 35 10 docs

Matched on EIF2S1 eIF2

Often named withMTOR PIK3CA (PI3K)AKT1 (Akt)APOE APP PSEN1

MFSD2A Vascular / BBB 35 6 docs

Matched on MFSD2A

Often named withAPOE LRP1 ABCB1 (P-gp)APP BACE1 CCL2 (MCP-1)

VCAN (versican) Reelin, synapse & ECM–PNN 35 23 docs

Matched on VCAN versican

Often named withACAN (aggrecan)PVALB (parvalbumin)MMP9 APOE BCAN (brevican)NCAN (neurocan)

ABCA1 GWAS / LOAD risk 34 16 docs

Matched on ABCA1

Often named withAPOE V-ATPase (ATP6V)APP PSEN1 TREM2 ACAT1

SIRT3 Bioenergetic / mito / NAD 34 11 docs

Matched on SIRT3

Often named withAPOE APP CD38 PARP1 PSEN1 SIRT1

KL (klotho) Trophic / exercise / resilience 33 9 docs

Matched on klotho

Often named withAPOE PP2A ABI3 ADAM10 APP BACE1

SRC Kinase & growth-factor signalling 33 13 docs

Matched on Src[- ]family Src kinases?

Often named withAPP DAB1 LRP8 (ApoER2)PSEN1 RELN APOE

MS4A GWAS / LOAD risk 32 9 docs

Matched on MS4A4A MS4A6A MS4A

Often named withCD33 TREM2 APOE PLCG2 ABI3 CX3CR1

NLRP1 Microglia & innate immunity 32 3 docs

Matched on NLRP1

Often named withAPP CASP1 CD36 CTSB GSDMD NEK7

GRIA1 (GluA1) Reelin, synapse & ECM–PNN 31 15 docs

Matched on GRIA1 GluA1 GluR1

Often named withAPOE APP PSEN1 DLG4 (PSD-95)TARDBP (TDP-43)PIK3CA (PI3K)

PICALM GWAS / LOAD risk 31 15 docs

Matched on PICALM

Often named withAPP PSEN1 APOE V-ATPase (ATP6V)SORL1 BIN1

PPP3CA (calcineurin) Kinase & growth-factor signalling 31 15 docs

Matched on PPP3CA calcineurin

Often named withAPOE APP PSEN1 TARDBP (TDP-43)BACE1 MTOR

TRPML1 Autophagy / lysosome / clearance 31 14 docs

Matched on TRPML1 MCOLN1

Often named withAPP PSEN1 V-ATPase (ATP6V)TFEB MTOR APOE

ADAMTS5 Reelin, synapse & ECM–PNN 30 10 docs

Matched on ADAMTS-?5

Often named withADAMTS4 ACAN (aggrecan)PVALB (parvalbumin)APOE APP MMP9

AGER (RAGE) Vascular / BBB 30 7 docs

Matched on AGER RAGE

Often named withAPOE APP MMP9 PVALB (parvalbumin)TREM2 ACAN (aggrecan)

APPL1 Autophagy / lysosome / clearance 30 6 docs

Matched on APPL1

Often named withAPOE APP PSEN1 BACE1 RAB5A V-ATPase (ATP6V)

CGAS Microglia & innate immunity 30 10 docs

Matched on cGAS CGAS

Often named withSTING APOE APP MTOR PRKN AKT1 (Akt)

SMPD1 (acid sphingomyelinase) Lipid, sterol & membrane 30 3 docs

Matched on SMPD1 acid sphingomyelinase ASMase

Often named withAPOE APP BACE1 PSEN1 ABCB1 (P-gp)BCL2 (Bcl-2)

TPH2 Neuromodulator / circadian / kynurenine 30 5 docs

Matched on TPH2

Often named withIDO1 ACAN (aggrecan)APOE APP BDNF HTR1A

SMPD3 Lipid, sterol & membrane 29 2 docs

Matched on SMPD3 neutral sphingomyelinase

Often named withAPOE APP BACE1 PP2A PSEN1 SMPD1 (acid sphingomyelinase)

ACSL4 Oxidative stress & ferroptosis 28 8 docs

Matched on ACSL4

Often named withAPOE APP PSEN1 TREM2 ABCA1 CR3

ARNTL (BMAL1) Neuromodulator / circadian / kynurenine 28 10 docs

Matched on BMAL1 ARNTL

Often named withAPOE C1QA C3 CR3 SORL1 AANAT

CYCS (cytochrome c) Bioenergetic / mito / NAD 28 10 docs

Matched on CYCS cytochrome c(?! oxidase)

Often named withAPP APOE PSEN1 TNF V-ATPase (ATP6V)BACE1

SALL1 Microglia & innate immunity 28 21 docs

Matched on SALL1

Often named withP2RY12 TMEM119 PVALB (parvalbumin)TREM2 ACAN (aggrecan)APOE

SSH1 (slingshot-1) Reelin, synapse & ECM–PNN 28 3 docs

Matched on SSH1 slingshot[- ]?1

Often named withC4 (complement)DLG4 (PSD-95)LILRB2 APOE APP ARHGEF15 (Ephexin5)

ABCA7 GWAS / LOAD risk 27 8 docs

Matched on ABCA7

Often named withAPP PSEN1 APOE BACE1 SORL1 TARDBP (TDP-43)

GRIN2B Reelin, synapse & ECM–PNN 27 13 docs

Matched on GRIN2B GluN2B NR2B

Often named withAPOE APP PSEN1 BDNF RELN LRP8 (ApoER2)

TLR4 Microglia & innate immunity 27 16 docs

Matched on TLR4

Often named withTREM2 TNF APP NLRP3 PSEN1 APOE

DYRK1A Amyloid & Tau core 26 2 docs

Matched on DYRK1A

Often named withACAN (aggrecan)APP C1QA C4 (complement)ADAMTS1 ADAMTS4

KCNC (Kv3) Neuromodulator / circadian / kynurenine 26 6 docs

Matched on Kv3 KCNC1 KCNC3

Often named withACAN (aggrecan)APP C1QA PSEN1 PVALB (parvalbumin)APOE

MEF2C GWAS / LOAD risk 26 5 docs

Matched on MEF2C

Often named withAPP APOE CD33 CX3CR1 PSEN1 STING

ROCK2 Reelin, synapse & ECM–PNN 26 7 docs

Matched on ROCK2

Often named withAPOE APP PSEN1 SORL1 ARHGEF15 (Ephexin5)C4 (complement)

SLC2A1 (GLUT1) Vascular / BBB 26 5 docs

Matched on GLUT1 SLC2A1

Often named withAPP AQP4 CLDN5 IL6 TNF ABCB1 (P-gp)

ABCB1 (P-gp) Vascular / BBB 25 8 docs

Matched on ABCB1 P-?glycoprotein

Often named withAPOE NFKB1 (NF-κB)APP IL6 TNF BACE1

CHI3L1 (YKL-40) Astrocyte & glial markers 25 5 docs

Matched on CHI3L1 YKL-?40

Often named withTREM2 APOE GFAP TNF IL6 NEFL (NfL)

CHRNA7 Neuromodulator / circadian / kynurenine 25 9 docs

Matched on CHRNA7 7 ?nAChR alpha-?7 nicotinic

Often named withACHE APP TNF APOE BIN1 CAMP (LL-37)

CLU GWAS / LOAD risk 25 12 docs

Matched on clusterin CLU

Often named withAPOE TREM2 APP C1QA C3 PSEN1

IL18 Microglia & innate immunity 25 13 docs

Matched on IL-?18

Often named withNLRP3 APP MTOR PSEN1 AKT1 (Akt)CASP1

NCAN (neurocan) Reelin, synapse & ECM–PNN 25 19 docs

Matched on NCAN neurocan

Often named withACAN (aggrecan)BCAN (brevican)MMP9 VCAN (versican)PVALB (parvalbumin)APOE

SNAP29 Autophagy / lysosome / clearance 25 7 docs

Matched on SNAP29

Often named withMTOR APP PSEN1 AKT1 (Akt)ATP13A2 (PARK9)BECN1

ABI3 GWAS / LOAD risk 24 13 docs

Matched on ABI3

Often named withAPOE PLCG2 TREM2 C3 CD33 C1QA

EIF2AK3 (PERK) Cell death & ER stress 24 12 docs

Matched on EIF2AK3 PERK

Often named withAPOE APP PSEN1 DLX1 TREM2 MTOR

NMNAT2 Bioenergetic / mito / NAD 24 6 docs

Matched on NMNAT2

Often named withADAMTS4 APP C1QA C3 GPX4 MMP9

QPRT Neuromodulator / circadian / kynurenine 24 2 docs

Matched on QPRT

Often named withAPOE ATF3 ATF4 CD38 CHAC1 DDIT3 (CHOP)

STING Microglia & innate immunity 24 11 docs

Matched on TMEM173 STING

Often named withCGAS APOE APP MTOR PRKN MAP1LC3B (LC3)

BCL2 (Bcl-2) Cell death & ER stress 23 11 docs

Matched on BCL2 Bcl-?2

Often named withAPOE APP PSEN1 MTOR BACE1 NLRP3

CDKN2A (p16) Epigenetic & senescence 23 3 docs

Matched on CDKN2A p16INK4a p16

Often named withCDKN1A (p21)FTH1/FTL (ferritin)NLRP3 APOE BCL2 (Bcl-2)BCL2L1 (Bcl-xL)

CD68 Microglia & innate immunity 22 11 docs

Matched on CD68

Often named withAPOE ACAN (aggrecan)TREM2 AIF1 (Iba1)GFAP P2RY12

ATP13A2 (PARK9) Autophagy / lysosome / clearance 21 6 docs

Matched on ATP13A2

Often named withAPP GBA MTOR PSEN1 V-ATPase (ATP6V)BECN1

CASP3 Cell death & ER stress 21 14 docs

Matched on CASP3 caspase-?3

Often named withAPOE PSEN1 BACE1 APP AKT1 (Akt)CAT (catalase)

CR1 GWAS / LOAD risk 21 10 docs

Matched on CR1

Often named withTREM2 APOE CD33 MTOR AKT1 (Akt)APP

FUS Neurodegeneration overlap 21 7 docs

Matched on FUS

Often named withAPP TARDBP (TDP-43)PSEN1 SOD1 APOE C9ORF72

MTHFR Trophic / exercise / resilience 21 5 docs

Matched on MTHFR

Often named withAPOE ABCA1 ABCA7 ABCB1 (P-gp)ABCG2 (BCRP)ABI3

SYK Microglia & innate immunity 21 11 docs

Matched on SYK

Often named withMTOR TREM2 CX3CR1 P2RY12 PIK3CA (PI3K)TYROBP

SYN1 (synapsin) Reelin, synapse & ECM–PNN 21 6 docs

Matched on SYN1 synapsin

Often named withAPOE APP LRP1 PRNP PSEN1 SOD1

TBK1 Microglia & innate immunity 21 4 docs

Matched on TBK1

Often named withAPOE APP C9ORF72 CTSD GBA GRN (progranulin)

TDO2 Neuromodulator / circadian / kynurenine 21 5 docs

Matched on TDO2 TDO

Often named withIDO1 APOE APP IDO2 KMO MTOR

CD200 Microglia & innate immunity 20 5 docs

Matched on CD200

Often named withACAN (aggrecan)APP CX3CR1 MMP9 PVALB (parvalbumin)BCAN (brevican)

CHAT (ChAT) Neuromodulator / circadian / kynurenine 20 7 docs

Matched on ChAT choline acetyltransferase

Often named withAPOE ACHE PARP1 ACAN (aggrecan)C1QA C3

DCX (doublecortin) Reelin, synapse & ECM–PNN 20 3 docs

Matched on DCX doublecortin

Often named withAPOE BDNF APP FNDC5 (irisin)PVALB (parvalbumin)SOX2

DNM1L Bioenergetic / mito / NAD 20 12 docs

Matched on DRP1 DNM1L

Often named withAPOE NFKB1 (NF-κB)NLRP3 SQSTM1 (p62)APP MTOR

HAPLN1 Reelin, synapse & ECM–PNN 20 10 docs

Matched on HAPLN1

Often named withACAN (aggrecan)TNR (tenascin-R)APP APOE BCAN (brevican)HAPLN4 (Bral2)

IAPP Neurodegeneration overlap 20 4 docs

Matched on IAPP amylin

Often named withMTOR NLRP3 IL6 NFKB1 (NF-κB)PSEN1 TNF

MMP3 Reelin, synapse & ECM–PNN 20 11 docs

Matched on MMP-?3

Often named withMMP9 PVALB (parvalbumin)ACAN (aggrecan)APOE ADAMTS4 BCAN (brevican)

TH (tyrosine hydroxylase) Neuromodulator / circadian / kynurenine 20 8 docs

Matched on tyrosine hydroxylase

Often named withAPP APOE PVALB (parvalbumin)ACAN (aggrecan)C1QA P2RY12

CD36 Microglia & innate immunity 19 9 docs

Matched on CD36

Often named withNLRP3 PSEN1 APP CASP1 CTSB PYCARD

IDE Amyloid & Tau core 19 8 docs

Matched on IDE

Often named withAPOE APP LRP1 PSEN1 SYN1 (synapsin)CD33

MAPK1/3 (ERK1/2) Kinase & growth-factor signalling 19 9 docs

Matched on MAPK[13] ERK1/2 ERK

Often named withAPP BDNF NTRK2 (TrkB)PSEN1 AKT1 (Akt)APOE

MBP (myelin basic protein) Myelin & axon inhibition 19 6 docs

Matched on MBP myelin basic protein

Often named withAPP MTOR PSEN1 SQSTM1 (p62)MAP1LC3B (LC3)PIK3CA (PI3K)

TOMM20 Bioenergetic / mito / NAD 19 8 docs

Matched on TOM20 TOMM20

Often named withAPP PINK1 APOE PRKN TOM40 MTOR

ATG5 Autophagy / lysosome / clearance 18 7 docs

Matched on ATG5

Often named withMTOR APP MAP1LC3B (LC3)NLRP3 SQSTM1 (p62)TNF

GRIN2A Reelin, synapse & ECM–PNN 18 7 docs

Matched on GRIN2A GluN2A NR2A

Often named withAPOE GRIN2B APP PSEN1 RELN BDNF

NDST1 Reelin, synapse & ECM–PNN 18 8 docs

Matched on NDST1

Often named withAPP DAB1 LRP8 (ApoER2)RELN ACAN (aggrecan)APOE

NPY Neuromodulator / circadian / kynurenine 18 9 docs

Matched on NPY neuropeptide Y

Often named withRELN SST (somatostatin)APOE DAB1 LRP8 (ApoER2)PSEN1

OTX2 Reelin, synapse & ECM–PNN 18 7 docs

Matched on OTX2

Often named withAPOE ACAN (aggrecan)MMP9 APP BCAN (brevican)DAB1

RIPK1 Cell death & ER stress 18 4 docs

Matched on RIPK1 RIP1 kinase

Often named withAPP BDNF C1QA C3 PSEN1 ADAMTS4

COL4A1 Vascular / BBB 17 1 doc

Matched on COL4A1

Often named withABCA1 ABCA7 ABCB1 (P-gp)ABCG2 (BCRP)ABI3 ACAN (aggrecan)

LIMK1 Reelin, synapse & ECM–PNN 17 6 docs

Matched on LIMK1

Often named withAPOE DAB1 DLG4 (PSD-95)GSK3B LRP8 (ApoER2)APP

MFN2 Bioenergetic / mito / NAD 17 8 docs

Matched on MFN2

Often named withAPOE APP PSEN1 BACE1 TARDBP (TDP-43)MTOR

PRKACA (PKA) Kinase & growth-factor signalling 17 12 docs

Matched on PRKACA PKA

Often named withAPOE APP PSEN1 V-ATPase (ATP6V)MMP9 MTOR

SLC18A2 (VMAT2) Neuromodulator / circadian / kynurenine 17 5 docs

Matched on SLC18A2 VMAT2

Often named withAPOE APP ACAN (aggrecan)PSEN1 DAB1 LRP8 (ApoER2)

SLC1A2 (EAAT2/GLT-1) Astrocyte & glial markers 17 6 docs

Matched on SLC1A2 EAAT2 GLT-?1

Often named withC1QA C3 NLRP3 ACAN (aggrecan)APOE APP

AIF1 (Iba1) Microglia & innate immunity 16 8 docs

Matched on AIF1 Iba-?1

Often named withAPOE CD68 GFAP TREM2 ACAN (aggrecan)P2RY12

CAT (catalase) Oxidative stress & ferroptosis 16 10 docs

Matched on catalase

Often named withAPOE PSEN1 BACE1 APP CASP3 TXNIP

DLX1 Reelin, synapse & ECM–PNN 16 7 docs

Matched on DLX1

Often named withAPOE APP EIF2AK3 (PERK)PSEN1 ABI3 C3

SLC40A1 (ferroportin) Oxidative stress & ferroptosis 16 5 docs

Matched on SLC40A1 ferroportin

Often named withGPX4 APOE APP NFE2L2 (NRF2)V-ATPase (ATP6V)LRP8 (ApoER2)

AXL Microglia & innate immunity 15 5 docs

Matched on AXL

Often named withAPOE C1QA C3 CLU CR3 FTH1/FTL (ferritin)

CDK5 Amyloid & Tau core 15 10 docs

Matched on CDK5

Often named withAPOE APP GSK3B PSEN1 BACE1 PP2A

HTR1A Neuromodulator / circadian / kynurenine 15 4 docs

Matched on HTR1A 5-?HT1A

Often named withBDNF IDO1 MAOA/MAOB NTRK2 (TrkB)TPH2 ACAN (aggrecan)

LAMP1 Autophagy / lysosome / clearance 15 7 docs

Matched on LAMP-?1

Often named withAPOE BACE1 APP CTSD MAP1LC3B (LC3)PSEN1

LDLR Lipid, sterol & membrane 15 10 docs

Matched on LDLR LDL receptor

Often named withAPOE APP LRP1 PSEN1 TARDBP (TDP-43)VLDLR

LPL Microglia & innate immunity 15 8 docs

Matched on LPL

Often named withAPOE NLRP3 TREM2 C1QA C3 CR3

P2RX7 Microglia & innate immunity 15 4 docs

Matched on P2RX7 P2X7

Often named withCASP1 NFKB1 (NF-κB)NLRP3 PYCARD ACAN (aggrecan)APP

PDGFRB Vascular / BBB 15 2 docs

Matched on PDGFRB PDGFR-?β

Often named withABCB1 (P-gp)ABCG2 (BCRP)AGER (RAGE)APOE APP AQP4

SLC17A8 (VGLUT3) Neuromodulator / circadian / kynurenine 15 2 docs

Matched on SLC17A8 VGLUT3

Often named withACAN (aggrecan)ADAM10 APP BDNF HTR1A HTR2A

TXN Oxidative stress & ferroptosis 15 8 docs

Matched on thioredoxin TXN

Often named withTXNIP APOE APP C1QA C3 ACAN (aggrecan)

TXNIP Microglia & innate immunity 15 9 docs

Matched on TXNIP

Often named withAPOE BACE1 CASP3 CAT (catalase)PSEN1 TXN

ATG7 Autophagy / lysosome / clearance 14 8 docs

Matched on ATG7

Often named withAPP TREM2 MAP1LC3B (LC3)MTOR PSEN1 APOE

CCL2 (MCP-1) Microglia & innate immunity 14 8 docs

Matched on CCL2 MCP-?1

Often named withAPOE IL6 MMP2 MMP9 NFKB1 (NF-κB)TNF

CDK3 Epigenetic & senescence 14 6 docs

Matched on CDK3

Often named withAPOE APP

INPP5D GWAS / LOAD risk 14 5 docs

Matched on INPP5D SHIP1

Often named withCD33 PSEN1 TREM2 ACAN (aggrecan)APP C1QA

NTRK1 (TrkA) Trophic / exercise / resilience 14 9 docs

Matched on NTRK1 TrkA

Often named withAPOE APP NGF PSEN1 BACE1 SQSTM1 (p62)

OLIG2 Down-syndrome chr21 14 3 docs

Matched on OLIG2

Often named withACAN (aggrecan)ADAMTS4 ADAMTS5 APOE APP BCAN (brevican)

PEMT Lipid, sterol & membrane 14 1 doc

Matched on PEMT

Often named withACHE ACSL1 APOE BHMT CHAT (ChAT)FLVCR2

RTN4R (NgR) Myelin & axon inhibition 14 8 docs

Matched on RTN4R NgR1? Nogo receptor

Often named withLILRB2 PIK3CA (PI3K)APOE APP AKT1 (Akt)C4 (complement)

SNAP47 Autophagy / lysosome / clearance 14 4 docs

Matched on SNAP47

Often named withMTOR SNAP29 ACOX1 AKT1 (Akt)APP ATP13A2 (PARK9)

STIM1 Cell death & ER stress 14 3 docs

Matched on STIM1

Often named withAPOE APP PSEN1 TARDBP (TDP-43)PSEN2 SORL1

SYP (synaptophysin) Reelin, synapse & ECM–PNN 14 11 docs

Matched on SYP synaptophysin

Often named withAPOE APP PSEN1 DLG4 (PSD-95)TREM2 BACE1

TMEM175 Autophagy / lysosome / clearance 14 5 docs

Matched on TMEM175

Often named withAPP GBA MTOR PSEN1 V-ATPase (ATP6V)ATP13A2 (PARK9)

VIP Neuromodulator / circadian / kynurenine 14 5 docs

Matched on VIP vasoactive intestinal peptide

Often named withAPP PVALB (parvalbumin)ACAN (aggrecan)C1QA PSEN1 SST (somatostatin)

DDIT3 (CHOP) Cell death & ER stress 13 6 docs

Matched on DDIT3 CHOP

Often named withAPOE ATF4 IL6 MTOR PARP1 TNF

FOXC1 Vascular / BBB 13 1 doc

Matched on FOXC1

Often named withABCA1 ABCA7 ABCB1 (P-gp)ABCG2 (BCRP)ABI3 ACAN (aggrecan)

HCAR2 (GPR109A) Bioenergetic / mito / NAD 13 2 docs

Matched on HCAR2 GPR109A HCA2

Often named withACAN (aggrecan)AKT1 (Akt)APOE APP BCAN (brevican)BDNF

HS3ST2 Reelin, synapse & ECM–PNN 13 4 docs

Matched on HS3ST2

Often named withAPOE APP DAB1 LRP1 LRP8 (ApoER2)PSEN1

HSPA1A (Hsp70) Cell death & ER stress 13 7 docs

Matched on HSPA1A Hsp70

Often named withAPP PINK1 PRKN MAP1LC3B (LC3)MTOR PRKAA (AMPK)

MSR1 Microglia & innate immunity 13 9 docs

Matched on MSR1

Often named withCD38 TREM2 ACAN (aggrecan)APP C4 (complement)CD33

NMRK1 Bioenergetic / mito / NAD 13 6 docs

Matched on NMRK1 NRK1

Often named withCD38 NAMPT PARP1 APOE ATF4 MTOR

S100B Reelin, synapse & ECM–PNN 13 2 docs

Matched on S100B S100β

Often named withAPP ACAN (aggrecan)ADAMTS1 ADAMTS4 ADAMTS5 AGER (RAGE)

SPP1 Microglia & innate immunity 13 8 docs

Matched on SPP1 osteopontin

Often named withAPOE TREM2 C1QA C3 C4 (complement)CX3CR1

VAMP8 Autophagy / lysosome / clearance 13 7 docs

Matched on VAMP8

Often named withTFEB V-ATPase (ATP6V)APOE APP BECN1 MTOR

VMA21 Autophagy / lysosome / clearance 13 2 docs

Matched on VMA21

Often named withAPP ATP13A2 (PARK9)EPG5 FYN GBA GRN (progranulin)

CAMK2A (CaMKII) Reelin, synapse & ECM–PNN 12 6 docs

Matched on CAMK2A CaMKII

Often named withAPP APOE PSEN1 PP2A PRKCA (PKC)RELN

CRP Microglia & innate immunity 12 6 docs

Matched on CRP C-?reactive protein

Often named withNLRP3 APP IL6 MTOR PRKAA (AMPK)PSEN1

CST7 (cystatin F) Microglia & innate immunity 12 9 docs

Matched on CST7 cystatin F

Often named withAPOE P2RY12 SALL1 TMEM119 TREM2 ACAN (aggrecan)

EP300 (p300) Epigenetic & senescence 12 5 docs

Matched on EP300 p300

Often named withAPOE APP NLRP3 PSEN1 ATG5 BACE1

GGA3 Autophagy / lysosome / clearance 12 2 docs

Matched on GGA3

Often named withAPP C4 (complement)CR3 DAB1 DLG4 (PSD-95)EPHB2

IL10 Microglia & innate immunity 12 9 docs

Matched on IL-?10

Often named withAPP TREM2 TNF APOE IL6 PSEN1

NEK7 Microglia & innate immunity 12 5 docs

Matched on NEK7

Often named withGSDMD NFKB1 (NF-κB)NLRP3 APP CASP1 CD36

NLRP2 Microglia & innate immunity 12 2 docs

Matched on NLRP2

Often named withAPP CASP1 CD36 CTSB GSDMD NEK7

SMAD3 Kinase & growth-factor signalling 12 7 docs

Matched on SMAD3

Often named withTREM2 ACAN (aggrecan)APOE CX3CR1 P2RY12 PVALB (parvalbumin)

TIMP1 Reelin, synapse & ECM–PNN 12 5 docs

Matched on TIMP-?1

Often named withMMP9 TARDBP (TDP-43)APOE APP C1QA C3

TMEM106B Autophagy / lysosome / clearance 12 2 docs

Matched on TMEM106B

Often named withAPOE APP BACE1 BECN1 C9ORF72 CD33

ABCG2 (BCRP) Vascular / BBB 11 3 docs

Matched on ABCG2 BCRP

Often named withABCB1 (P-gp)AGER (RAGE)APOE AQP4 BACE2 CCL2 (MCP-1)

C5AR1 Microglia & innate immunity 11 6 docs

Matched on C5aR C5AR1

Often named withTREM2 APOE NLRP3 APP C1QA NFKB1 (NF-κB)

DEGS1 Lipid, sterol & membrane 11 2 docs

Matched on DEGS1

Often named withABCA7 APOE APP PSEN1 SORL1 ABCA1

FOXP3 Microglia & innate immunity 11 2 docs

Matched on FOXP3

Often named withAPOE APP CD4 CLDN5 CLU LRP1

HAPLN4 (Bral2) Reelin, synapse & ECM–PNN 11 8 docs

Matched on HAPLN4 Bral2

Often named withACAN (aggrecan)BCAN (brevican)HAPLN1 MMP9 NCAN (neurocan)PVALB (parvalbumin)

HAS1/2/3 Reelin, synapse & ECM–PNN 11 5 docs

Matched on HAS1 HAS2 HAS3 hyaluronan synthase

Often named withACAN (aggrecan)APOE BCAN (brevican)HAPLN1 HAPLN4 (Bral2)MMP2

IGF1 Trophic / exercise / resilience 11 9 docs

Matched on IGF-?1

Often named withAPOE APP PSEN1 ATG5 BDNF IL18

ITGAX Microglia & innate immunity 11 8 docs

Matched on ITGAX CD11c

Often named withAPOE CST7 (cystatin F)P2RY12 SALL1 TMEM119 TREM2

PTGS2 (COX-2) Microglia & innate immunity 11 7 docs

Matched on PTGS2 COX-?2

Often named withAPOE MME (neprilysin)ACAN (aggrecan)APP BCAN (brevican)C1QA

SOAT1 Lipid, sterol & membrane 11 6 docs

Matched on SOAT1

Often named withACAT1 APOE APP PSEN1 ABCA1 LRP1

TIMM23 Bioenergetic / mito / NAD 11 3 docs

Matched on TIM23 TIMM23

Often named withAPOE APP CYCS (cytochrome c)HSD17B10 PINK1 TOM40

BNIP3L (NIX) Bioenergetic / mito / NAD 10 3 docs

Matched on BNIP3L NIX

Often named withACAN (aggrecan)AKT1 (Akt)APP IL18 MTOR NFE2L2 (NRF2)

CD2AP GWAS / LOAD risk 10 5 docs

Matched on CD2AP

Often named withAPOE APP BACE1 BIN1 PICALM SORL1

CD4 Microglia & innate immunity 10 3 docs

Matched on CD4

Often named withIL6 TNF ACE2 APP ATG16L1 ATG5

GLP1R Neuromodulator / circadian / kynurenine 10 5 docs

Matched on GLP-?1R GLP-?1 receptor

Often named withAKT1 (Akt)MTOR PIK3CA (PI3K)TREM2 V-ATPase (ATP6V)ACAN (aggrecan)

HEXB Autophagy / lysosome / clearance 10 9 docs

Matched on HEXB

Often named withCX3CR1 P2RY12 PVALB (parvalbumin)SALL1 TMEM119 TREM2

LEP (leptin) Neuromodulator / circadian / kynurenine 10 2 docs

Matched on LEP leptin

Often named withCAMP (LL-37)CHAT (ChAT)CHRNA7 GHRL (ghrelin)NFKB1 (NF-κB)PARP1

RAB7A Autophagy / lysosome / clearance 10 5 docs

Matched on RAB7A Rab7

Often named withAPP CTSD GBA MTOR PSEN1 TARDBP (TDP-43)

RELCH Autophagy / lysosome / clearance 10 5 docs

Matched on RELCH KIAA1468

Often named withAPOE CAV1 (caveolin-1)APP BACE1 LRP1 ABCA1

RORB Reelin, synapse & ECM–PNN 10 2 docs

Matched on RORB

Often named withACAN (aggrecan)APOE APP BCAN (brevican)C1QA C3

SMAD7 Kinase & growth-factor signalling 10 6 docs

Matched on SMAD7

Often named withACAN (aggrecan)ADAMTS4 C4 (complement)LILRB2 MMP9 PVALB (parvalbumin)

VCP Neurodegeneration overlap 10 5 docs

Matched on VCP

Often named withAPOE APP PINK1 V-ATPase (ATP6V)C9ORF72 CTSD

VDAC1 Bioenergetic / mito / NAD 10 3 docs

Matched on VDAC1 VDAC

Often named withAPOE APP BACE1 BAX CYCS (cytochrome c)GSK3B

VDR Neuromodulator / circadian / kynurenine 10 3 docs

Matched on VDR vitamin D receptor

Often named withAPOE APP MTOR NLRP3 PRKAA (AMPK)PSEN1

ADAMTS1 Reelin, synapse & ECM–PNN 9 4 docs

Matched on ADAMTS-?1

Often named withACAN (aggrecan)ADAMTS4 BCAN (brevican)MMP9 PVALB (parvalbumin)APOE

BAX Cell death & ER stress 9 4 docs

Matched on BAX

Often named withAPOE APP PSEN1 BACE1 ACAN (aggrecan)BCL2 (Bcl-2)

CD22 Microglia & innate immunity 9 1 doc

Matched on CD22

Often named withACAN (aggrecan)ADRB (β-AR)APP BCAN (brevican)C1QA C3AR1

CLEC7A (dectin-1) Microglia & innate immunity 9 6 docs

Matched on CLEC7A dectin-?1

Often named withAPOE CX3CR1 MMP9 P2RY12 TREM2 C1QA

DNM2 Autophagy / lysosome / clearance 9 8 docs

Matched on DNM2

Often named withAPOE BIN1 APP ATP synthase (ATP5x)BECN1 CD38

GAD1 (GAD67) Reelin, synapse & ECM–PNN 9 3 docs

Matched on GAD1 GAD67

Often named withAPP PSEN1 PVALB (parvalbumin)ABCA1 ABCA7 ABI3

HTR2A Neuromodulator / circadian / kynurenine 9 4 docs

Matched on HTR2A 5-?HT2A

Often named withTARDBP (TDP-43)BDNF HTR1A IDO1 MAOA/MAOB NTRK2 (TrkB)

IL1B Microglia & innate immunity 9 5 docs

Matched on IL-?1β IL-?1beta IL1B IL-?1b

Often named withTNF TREM2 AKT1 (Akt)APP IL6 MTOR

MRC1 (CD206) Microglia & innate immunity 9 6 docs

Matched on MRC1 CD206

Often named withAPOE CD163 MMP9 TREM2 CR1 CX3CR1

NOS2 (iNOS) Microglia & innate immunity 9 4 docs

Matched on NOS2 iNOS

Often named withACAN (aggrecan)APP IL6 P2RY12 PSEN1 TNF

PPARGC1A Bioenergetic / mito / NAD 9 1 doc

Matched on PPARGC1A PGC-?1α PGC-?1alpha PGC-?1a

Often named withACAN (aggrecan)AKT1 (Akt)APOE APP ATP synthase (ATP5x)ATP2A2 (SERCA2)

PPIF (cyclophilin D) Bioenergetic / mito / NAD 9 4 docs

Matched on PPIF cyclophilin[- ]?D CypD

Often named withAPP APOE CYCS (cytochrome c)HSD17B10 ADAM10 APOC1

PRKCA (PKC) Kinase & growth-factor signalling 9 6 docs

Matched on PRKCA PKC

Often named withAPOE APP AKT1 (Akt)BDNF GRIN2A GRIN2B

SLC7A11 (xCT) Oxidative stress & ferroptosis 9 5 docs

Matched on SLC7A11 xCT

Often named withAPOE NFE2L2 (NRF2)AIFM2 (FSP1)ALOX15 APP FTH1/FTL (ferritin)

SOD2 Oxidative stress & ferroptosis 9 4 docs

Matched on SOD2

Often named withAPP CD38 MTOR NFE2L2 (NRF2)P2RY12 PARP1

STAT (1/3/6) Microglia & innate immunity 9 5 docs

Matched on STAT1 STAT3 STAT6

Often named withAKT1 (Akt)APOE APP BDNF IL6 MTOR

VPS26 Autophagy / lysosome / clearance 9 5 docs

Matched on VPS26

Often named withAPOE APP PSEN1 SORL1 VPS35 TREM2

ALOX15 Oxidative stress & ferroptosis 8 5 docs

Matched on ALOX15 15-LOX

Often named withAPOE GPX4 AIFM2 (FSP1)NFE2L2 (NRF2)PSEN1 SLC7A11 (xCT)

ASAH1 (acid ceramidase) Lipid, sterol & membrane 8 1 doc

Matched on ASAH1 acid ceramidase

Often named withABCA7 APOE APP BACE1 BAX BCL2 (Bcl-2)

CD74 Microglia & innate immunity 8 3 docs

Matched on CD74

Often named withMIF

CTNNB1 (β-catenin) Kinase & growth-factor signalling 8 5 docs

Matched on CTNNB1 catenin

Often named withAPP APOE PSEN1 AKT1 (Akt)C4 (complement)PIK3CA (PI3K)

HAMP (hepcidin) Oxidative stress & ferroptosis 8 1 doc

Matched on HAMP hepcidin

Often named withAIFM2 (FSP1)ALOX15 APOE APP ATP synthase (ATP5x)CD38

HMOX1 Oxidative stress & ferroptosis 8 3 docs

Matched on HMOX1 HO-1 heme oxygenase

Often named withAPOE FTH1/FTL (ferritin)GPX4 NFE2L2 (NRF2)AIFM2 (FSP1)ALOX15

INSR Neuromodulator / circadian / kynurenine 8 6 docs

Matched on INSR insulin receptor

Often named withAPP PSEN1 APOE LRP1 MTOR DAB1

MLKL Cell death & ER stress 8 2 docs

Matched on MLKL

Often named withADAMTS4 APP BDNF C1QA C3 GPX4

OPA1 Bioenergetic / mito / NAD 8 4 docs

Matched on OPA1

Often named withAPOE APP DNM1L PSEN1 SQSTM1 (p62)ACAN (aggrecan)

PDHA1 (PDH) Bioenergetic / mito / NAD 8 5 docs

Matched on PDHA1 pyruvate dehydrogenase

Often named withMTOR AKT1 (Akt)APP PIK3CA (PI3K)PRKAA (AMPK)PSEN1

PLG (plasminogen) Vascular / BBB 8 4 docs

Matched on PLG plasminogen

Often named withAPOE APP LRP1 PSEN1 VLDLR DAB1

PPP1CA (PP1) Kinase & growth-factor signalling 8 8 docs

Matched on PPP1CA PP1

Often named withAPP APOE PSEN1 AKT1 (Akt)MTOR BECN1

SATB1 Epigenetic & senescence 8 3 docs

Matched on SATB1

Often named withAPOE NLRP3 ACAN (aggrecan)APP BCAN (brevican)C1QA

SLC7A5 (LAT1) Vascular / BBB 8 4 docs

Matched on SLC7A5 LAT1

Often named withAPOE IL6 PARP1 TNF ABCB1 (P-gp)ABCG2 (BCRP)

SMAD2 Kinase & growth-factor signalling 8 6 docs

Matched on SMAD2

Often named withCX3CR1 P2RY12 TMEM119 TREM2 ACAN (aggrecan)APOE

TFAM Bioenergetic / mito / NAD 8 4 docs

Matched on TFAM

Often named withACAN (aggrecan)APP MTOR NFE2L2 (NRF2)P2RY12 PIK3CA (PI3K)

TFE3 Autophagy / lysosome / clearance 8 5 docs

Matched on TFE3

Often named withMTOR PSEN1 APOE APP GBA GRN (progranulin)

TP53 (p53) Epigenetic & senescence 8 6 docs

Matched on TP53 p53

Often named withCD38 MTOR NFKB1 (NF-κB)PARP1 APOE CDKN1A (p21)

VEGF Trophic / exercise / resilience 8 6 docs

Matched on VEGF

Often named withAPP APOE CAMK2A (CaMKII)GFAP HIF1A IL6

ACSL1 Lipid, sterol & membrane 7 5 docs

Matched on ACSL1

Often named withAPOE CTSB DGAT2 NLRP3 PLIN2 (perilipin-2)SPP1

ADAMTS2 Reelin, synapse & ECM–PNN 7 6 docs

Matched on ADAMTS-?2

Often named withACAN (aggrecan)TNR (tenascin-R)TREM2 VCAN (versican)APOE PVALB (parvalbumin)

CD47 Microglia & innate immunity 7 2 docs

Matched on CD47

Often named withAPP C1QA PSEN1 RELN SIRPA TREM2

CHL1 Reelin, synapse & ECM–PNN 7 5 docs

Matched on CHL1

Often named withAPOE APP BACE1 GSK3B PSEN1 AKT1 (Akt)

DBH Neuromodulator / circadian / kynurenine 7 3 docs

Matched on DBH dopamine β-hydroxylase

Often named withACAN (aggrecan)ACSL4 APOE APP BCAN (brevican)CX3CR1

FANCC Epigenetic & senescence 7 2 docs

Matched on FANCC

Often named withACOX1 AKT1 (Akt)ATF4 BCL2 (Bcl-2)BECN1 CGAS

FLVCR2 Vascular / BBB 7 1 doc

Matched on FLVCR2

Often named withACHE ACSL1 APOE BHMT CHAT (ChAT)MFSD2A

HEXIM1 Epigenetic & senescence 7 7 docs

Matched on HEXIM1

Often named withAPOE SORL1

HSF1 Cell death & ER stress 7 2 docs

Matched on HSF1

Often named withABCB1 (P-gp)APOE APP BACE1 BCL2 (Bcl-2)BDNF

ICAM1 Vascular / BBB 7 4 docs

Matched on ICAM-?1

Often named withIL6 NFKB1 (NF-κB)TNF VCAM1 DDIT3 (CHOP)MTOR

IDO2 Neuromodulator / circadian / kynurenine 7 4 docs

Matched on IDO2

Often named withAPOE IDO1 KMO TDO2 TPH2 ACAN (aggrecan)

LILRB5 GWAS / LOAD risk 7 2 docs

Matched on LILRB5

Often named withC1QA C3 C4 (complement)CR3 DLG4 (PSD-95)LILRB2

MAP2 Reelin, synapse & ECM–PNN 7 5 docs

Matched on MAP2

Often named withAPOE APP BACE1 PSEN1 DLG4 (PSD-95)SYP (synaptophysin)

MAPK8 (JNK) Kinase & growth-factor signalling 7 4 docs

Matched on MAPK8 JNK

Often named withAKT1 (Akt)APOE APP BDNF MAPK14 (p38)NGF

NQO2 Oxidative stress & ferroptosis 7 3 docs

Matched on NQO2

Often named withAPP ATP synthase (ATP5x)PSEN1 CD38 GPX4 MTOR

NRG1 (neuregulin-1) Reelin, synapse & ECM–PNN 7 5 docs

Matched on NRG1 neuregulin-?1

Often named withAPOE APP BACE1 PIK3CA (PI3K)AKT1 (Akt)CLU

OGDH (KGDH) Bioenergetic / mito / NAD 7 2 docs

Matched on OGDH KGDH ketoglutarate dehydrogenase

Often named withAPOE APP CAT (catalase)IGF1 PDHA1 (PDH)PRKAA (AMPK)

RIPK3 Cell death & ER stress 7 2 docs

Matched on RIPK3

Often named withADAMTS4 APP BDNF C1QA C3 GPX4

SIRPA Microglia & innate immunity 7 2 docs

Matched on SIRPA SIRP

Often named withAPP C1QA CD47 PSEN1 RELN TREM2

SIRT6 Bioenergetic / mito / NAD 7 4 docs

Matched on SIRT6

Often named withSIRT1 APOE APP P2RY12 PARP1 PSEN1

SIRT7 Bioenergetic / mito / NAD 7 4 docs

Matched on SIRT7

Often named withCD38 NAMPT PARP1 SIRT1 SIRT3 APOE

TFRC Oxidative stress & ferroptosis 7 4 docs

Matched on TFRC transferrin receptor

Often named withAPOE APP PSEN1 AIFM2 (FSP1)ALOX15 BACE1

TLR2 Microglia & innate immunity 7 4 docs

Matched on TLR2

Often named withCD36 TLR4 ACAN (aggrecan)CTSB NFKB1 (NF-κB)NLRP3

VPS29 Autophagy / lysosome / clearance 7 4 docs

Matched on VPS29

Often named withAPOE APP PSEN1 SORL1 VPS26 VPS35

VPS41 Autophagy / lysosome / clearance 7 2 docs

Matched on VPS41

Often named withAPP ATP13A2 (PARK9)EPG5 FYN GBA GRN (progranulin)

ACOX1 Lipid, sterol & membrane 6 3 docs

Matched on ACOX1

Often named withAKT1 (Akt)BECN1 EIF2S1 (eIF2α)MTOR PPP1CA (PP1)SNAP29

ADRB (β-AR) Neuromodulator / circadian / kynurenine 6 1 doc

Matched on ADRB1 ADRB2 β[12]?-AR β-adrenergic

Often named withACAN (aggrecan)APP BCAN (brevican)C1QA C3AR1 C5AR1

AOAH Microglia & innate immunity 6 6 docs

Matched on AOAH

Often named withAPOE NFKB1 (NF-κB)

APAF1 Cell death & ER stress 6 6 docs

Matched on APAF1 Apaf-?1

Often named withPSEN1 APOE BACE1 CASP3 CAT (catalase)TXNIP

ATP2A2 (SERCA2) Cell death & ER stress 6 3 docs

Matched on ATP2A2 SERCA

Often named withAPOE PSEN1 V-ATPase (ATP6V)APP MAP1LC3B (LC3)PICALM

CD14 Microglia & innate immunity 6 4 docs

Matched on CD14

Often named withAPOE APP MTOR PSEN1 TREM2 CAMP (LL-37)

CD163 Microglia & innate immunity 6 6 docs

Matched on CD163

Often named withAPOE MMP9 MRC1 (CD206)PVALB (parvalbumin)TREM2 C1QA

CHST3 Reelin, synapse & ECM–PNN 6 3 docs

Matched on CHST3

Often named withACAN (aggrecan)ADAMTS4 APOE APP BCAN (brevican)C1QA

EPHA1 GWAS / LOAD risk 6 3 docs

Matched on EPHA1

Often named withABCA7 APOE APP ATG7 BACE1 BIN1

FASN Lipid, sterol & membrane 6 3 docs

Matched on FASN fatty acid synthase

Often named withAPP PSEN1 APOE ATP synthase (ATP5x)PARP1 ACAN (aggrecan)

FGA/FGB/FGG (fibrinogen) Vascular / BBB 6 3 docs

Matched on FGA FGB FGG fibrinogen

Often named withIL6 MMP9 ABCB1 (P-gp)ABCG2 (BCRP)AGER (RAGE)APOE

GRAMD1B (Aster-B) Lipid, sterol & membrane 6 2 docs

Matched on GRAMD1B Aster-?B

Often named withACAT1 APOE APP CAV1 (caveolin-1)DAB1 GRIN2A

HDAC6 Epigenetic & senescence 6 3 docs

Matched on HDAC6

Often named withAPOE APP BACE1 GSK3B TREM2 V-ATPase (ATP6V)

LPCAT3 Lipid, sterol & membrane 6 3 docs

Matched on LPCAT3

Often named withACSL4 AIFM2 (FSP1)ALOX15 ALOX5 APOE C1QA

MFN1 Bioenergetic / mito / NAD 6 4 docs

Matched on MFN1 mitofusin-?1

Often named withAPOE APP BACE1 DNM1L PSEN1 SOD1

NGFR (p75NTR) Trophic / exercise / resilience 6 3 docs

Matched on NGFR p75-?NTR p75 neurotrophin receptor

Often named withBACE1 ABCB1 (P-gp)ACE2 AKT1 (Akt)APOE APP

NOS3 (eNOS) Vascular / BBB 6 1 doc

Matched on NOS3 eNOS

Often named withATG16L1 ATG5 CASP1 CD4 CDKN1A (p21)CGAS

PLEKHM1 Autophagy / lysosome / clearance 6 3 docs

Matched on PLEKHM1

Often named withAKT1 (Akt)BECN1 EIF2S1 (eIF2α)MTOR SNAP29 ACOX1

PLP1 Myelin & axon inhibition 6 3 docs

Matched on PLP1

Often named withAPP ATG7 EIF2AK3 (PERK)GFAP MAP1LC3B (LC3)MBP (myelin basic protein)

RAB11A Autophagy / lysosome / clearance 6 4 docs

Matched on RAB11A Rab11

Often named withAPP PSEN1 TARDBP (TDP-43)APOE CTSD MAP1LC3B (LC3)

RAC1 Reelin, synapse & ECM–PNN 6 4 docs

Matched on RAC1

Often named withAPOE APP PRNP RHOA AKT1 (Akt)ARHGEF15 (Ephexin5)

ROCK1 Reelin, synapse & ECM–PNN 6 4 docs

Matched on ROCK1

Often named withAPP C4 (complement)DAB1 LILRB2 LRP8 (ApoER2)PSEN1

SLC5A7 (CHT1) Neuromodulator / circadian / kynurenine 6 1 doc

Matched on SLC5A7 CHT1

Often named withACHE ACSL1 APOE BHMT CHAT (ChAT)FLVCR2

STX17 (syntaxin-17) Autophagy / lysosome / clearance 6 3 docs

Matched on STX17 syntaxin-?17

Often named withMTOR PRKN SNAP29 VAMP8 APP ATP13A2 (PARK9)

TGFB1 Kinase & growth-factor signalling 6 6 docs

Matched on TGFB1 TGF-?β1 TGF-?beta1

Often named withAPOE TREM2 ACAN (aggrecan)MTOR PVALB (parvalbumin)ADAMTS4

VAPB Neurodegeneration overlap 6 2 docs

Matched on VAPB

Often named withAPOE APP BACE1 BAX GSK3B MFN2

VPS4A Autophagy / lysosome / clearance 6 5 docs

Matched on VPS4A

Often named withAPOE APP PSEN1 BACE1 MTOR TREM2

ZBP1 Microglia & innate immunity 6 1 doc

Matched on ZBP1

Often named withAPOE APP CD14 CGAS CST3 (cystatin C)EP300 (p300)

AANAT Neuromodulator / circadian / kynurenine 5 3 docs

Matched on AANAT

Often named withAPOE AKT1 (Akt)ATF4 BDNF CD38 CYCS (cytochrome c)

ALOX5 Oxidative stress & ferroptosis 5 4 docs

Matched on ALOX5 5-?LOX

Often named withAPOE C1QA C3 CLU CR3 GPX4

CHST11 Reelin, synapse & ECM–PNN 5 3 docs

Matched on CHST11

Often named withACAN (aggrecan)ADAMTS4 APOE APP BCAN (brevican)C1QA

CRH Neuromodulator / circadian / kynurenine 5 2 docs

Matched on CRH corticotropin[- ]releasing hormone

Often named withAKT1 (Akt)APOE APP BDNF MAPK1/3 (ERK1/2)MMP9

DGAT2 Lipid, sterol & membrane 5 4 docs

Matched on DGAT2

Often named withACSL1 APOE CTSB NLRP3 SPP1 TREM2

EPG5 Autophagy / lysosome / clearance 5 2 docs

Matched on EPG5

Often named withAPP ATP13A2 (PARK9)FYN GBA GRN (progranulin)MTOR

GAD2 (GAD65) Reelin, synapse & ECM–PNN 5 2 docs

Matched on GAD2 GAD65

Often named withABCA1 ABCA7 ABI3 ACAN (aggrecan)ACSL4 ADAMTS4

GAS6 Microglia & innate immunity 5 3 docs

Matched on GAS6

Often named withACAN (aggrecan)ADAMTS4 APOE C1QA C3 C4 (complement)

GCLC Oxidative stress & ferroptosis 5 3 docs

Matched on GCLC

Often named withACSL4 AIFM2 (FSP1)ALOX15 ALOX5 APOE C1QA

GPHN (gephyrin) Reelin, synapse & ECM–PNN 5 2 docs

Matched on GPHN gephyrin

Often named withABCA1 ABCA7 ABI3 ACAN (aggrecan)ACSL4 ADAMTS4

HSP90AA1 (Hsp90) Cell death & ER stress 5 3 docs

Matched on HSP90AA1 Hsp90

Often named withAPP HSPA1A (Hsp70)PINK1 PRKN APOE BACE1

IFNAR1/2 Down-syndrome chr21 5 2 docs

Matched on IFNAR1 IFNAR2 IFNAR

Often named withAPOE APP C1QA C3 CR3 GSK3B

ITM2B (BRI2) Amyloid & Tau core 5 2 docs

Matched on ITM2B BRI2

Often named withABI3 APOE APP C3 CLU EIF2AK3 (PERK)

ITPR1 (IP3R) Cell death & ER stress 5 2 docs

Matched on ITPR1 IP3 ?receptor IP3R

Often named withAPOE APP BACE1 GSK3B PPP3CA (calcineurin)PSEN1

JAK2 Microglia & innate immunity 5 1 doc

Matched on JAK2

Often named withAANAT ABCB1 (P-gp)ACAN (aggrecan)ACHE ADAMTS4 AKT1 (Akt)

KEAP1 Oxidative stress & ferroptosis 5 2 docs

Matched on KEAP1

Often named withALOX5 APOE C1QA C3 CHI3L1 (YKL-40)CLU

LMNB1 Epigenetic & senescence 5 4 docs

Matched on LMNB1 lamin B1

Often named withACAN (aggrecan)APOE BCAN (brevican)BCL2 (Bcl-2)BCL2L1 (Bcl-xL)CCL2 (MCP-1)

MOG Myelin & axon inhibition 5 2 docs

Matched on MOG myelin oligodendrocyte glycoprotein

Often named withABCA1 ABCA7 ABI3 ACAN (aggrecan)ACSL4 ADAMTS4

NMRK2 Bioenergetic / mito / NAD 5 4 docs

Matched on NMRK2 NRK2

Often named withAPP CD38 GPX4 MTOR NAMPT NFE2L2 (NRF2)

NPTX2 Reelin, synapse & ECM–PNN 5 3 docs

Matched on NPTX2 Narp

Often named withACAN (aggrecan)APOE BCAN (brevican)MMP9 NCAN (neurocan)PVALB (parvalbumin)

PARL Bioenergetic / mito / NAD 5 3 docs

Matched on PARL

Often named withAPP PINK1 PRKN ACAN (aggrecan)AKT1 (Akt)APOE

PLD3 GWAS / LOAD risk 5 3 docs

Matched on PLD3

Often named withACAN (aggrecan)ADAMTS4 APOE BACE1 GFAP MMP2

POLG Bioenergetic / mito / NAD 5 2 docs

Matched on POLG

Often named withABCA1 ABCA7 ABI3 ACAN (aggrecan)ACSL4 ADAMTS4

SYNJ1 Down-syndrome chr21 5 1 doc

Matched on SYNJ1

Often named withACAN (aggrecan)ADAMTS1 ADAMTS4 ADAMTS5 AGER (RAGE)APOE

TSPO Microglia & innate immunity 5 3 docs

Matched on TSPO translocator protein

Often named withAPOE APP PRKAA (AMPK)PSEN1 ACAN (aggrecan)AKT1 (Akt)

WDR91 Autophagy / lysosome / clearance 5 2 docs

Matched on WDR91

Often named withAPP ATP13A2 (PARK9)EPG5 FYN GBA GRN (progranulin)

APBB1 Amyloid & Tau core 4 1 doc

Matched on APBB1 Fe65

Often named withABI3 ADAM10 AKT1 (Akt)APLP2 APOE APP

APLP1 Amyloid & Tau core 4 2 docs

Matched on APLP1

Often named withAPOE APP BACE1 CHL1 PSEN1 ROCK2

APOC1 GWAS / LOAD risk 4 2 docs

Matched on APOC1

Often named withADAM10 APOE APP ATAD1 (Thorase)CYCS (cytochrome c)HSD17B10

CASP8 Cell death & ER stress 4 2 docs

Matched on CASP8 caspase-?8

Often named withAPP BIN1 C1QA C3 CASP1 CASP9

CCR5 Microglia & innate immunity 4 2 docs

Matched on CCR5

Often named withTARDBP (TDP-43)TNF ACE2 APP ATG5 ATG9A

CSNK1D (CK1δ) Kinase & growth-factor signalling 4 2 docs

Matched on CSNK1D CK1 casein kinase 1

Often named withABCA7 AKT1 (Akt)APOE APP BACE1 DAB1

ERBB4 Reelin, synapse & ECM–PNN 4 2 docs

Matched on ERBB4

Often named withABCA1 ABCA7 ABI3 ACAN (aggrecan)ACSL4 ADAMTS4

FKBP5 Neuromodulator / circadian / kynurenine 4 2 docs

Matched on FKBP5

Often named withAKT1 (Akt)APP CASP1 IL18 IL6 MTOR

GAP43 Reelin, synapse & ECM–PNN 4 1 doc

Matched on GAP-?43

Often named withAPP CHI3L1 (YKL-40)GFAP NEFL (NfL)NRGN (neurogranin)PSEN1

GPX1 Oxidative stress & ferroptosis 4 3 docs

Matched on GPX1

Often named withAIFM2 (FSP1)ALOX15 APOE FTH1/FTL (ferritin)GPX4 NFE2L2 (NRF2)

H2AX Epigenetic & senescence 4 2 docs

Matched on H2AX

Often named withBCL2 (Bcl-2)BCL2L1 (Bcl-xL)CCL2 (MCP-1)CD38 CDKN1A (p21)CDKN2A (p16)

HK1 Bioenergetic / mito / NAD 4 4 docs

Matched on HK1 hexokinase-? ?1

Often named withAPOE DNM1L NFKB1 (NF-κB)NLRP3

JAK1 Microglia & innate immunity 4 3 docs

Matched on JAK1

Often named withAPOE BDNF GRIN2B MAOA/MAOB STAT (1/3/6)AANAT

LHX6 Reelin, synapse & ECM–PNN 4 2 docs

Matched on LHX6

Often named withABCA1 ABCA7 ABI3 ACAN (aggrecan)ACSL4 ADAMTS4

LPCAT4 Lipid, sterol & membrane 4 2 docs

Matched on LPCAT4

Often named withABCA1 ABCA7 ACAT1 ACSL4 APOE APP

MCU Bioenergetic / mito / NAD 4 2 docs

Matched on MCU mitochondrial calcium uniporter

Often named withAPP GBA MTOR OPTN PICALM PINK1

NAPRT Bioenergetic / mito / NAD 4 4 docs

Matched on NAPRT

Often named withCD38 MTOR NAMPT NMRK1 PARP1 APOE

PLIN2 (perilipin-2) Lipid, sterol & membrane 4 4 docs

Matched on PLIN2 perilipin-?2

Often named withACSL1 APOE ACAN (aggrecan)C1QA C3 C4 (complement)

PROS1 Microglia & innate immunity 4 2 docs

Matched on PROS1

Often named withABI3 ACAN (aggrecan)ACSL1 ADAMTS4 AKT1 (Akt)APOE

PTEN Kinase & growth-factor signalling 4 4 docs

Matched on PTEN

Often named withAPP MTOR PSEN1 TARDBP (TDP-43)CTSD GBA

RECK Reelin, synapse & ECM–PNN 4 2 docs

Matched on RECK

Often named withABCA1 ABCA7 ABI3 ACAN (aggrecan)ACSL4 ADAMTS4

RILPL1 Autophagy / lysosome / clearance 4 2 docs

Matched on RILPL1

Often named withAPP ATP13A2 (PARK9)CTSD FYN GBA LRRK2

SHH Kinase & growth-factor signalling 4 3 docs

Matched on sonic hedgehog Shh

Often named withAPOE PVALB (parvalbumin)ABCB1 (P-gp)ABCG2 (BCRP)AGER (RAGE)APP

SLC6A3 (DAT) Neuromodulator / circadian / kynurenine 4 1 doc

Matched on SLC6A3 DAT

Often named withAPP CAV1 (caveolin-1)GAD1 (GAD67)MAOA/MAOB NLRP3 PSEN1

SUMF1 Autophagy / lysosome / clearance 4 2 docs

Matched on SUMF1

Often named withAPP LRRK2 MTOR PRKN PSEN1 SNCA

TAX1BP1 Autophagy / lysosome / clearance 4 4 docs

Matched on TAX1BP1

Often named withAPP MTOR OPTN PINK1 PRKN PSEN1

TBC1D24 Neurodegeneration overlap 4 2 docs

Matched on TBC1D24

Often named withAPP ATP13A2 (PARK9)EPG5 FYN GBA GRN (progranulin)

TET1/2/3 Epigenetic & senescence 4 1 doc

Matched on TET1 TET2 TET3

Often named withABI3 ADAM10 APOE APP BACE1 CD33

TGFBR1 Kinase & growth-factor signalling 4 3 docs

Matched on TGFBR1

Often named withAPOE APP CR3 P2RY12 PVALB (parvalbumin)SALL1

TIMP2 Reelin, synapse & ECM–PNN 4 3 docs

Matched on TIMP-?2

Often named withACAN (aggrecan)ADAMTS4 APOE APP BCAN (brevican)C1QA

TLR6 Microglia & innate immunity 4 2 docs

Matched on TLR6

Often named withAPP CASP1 CD36 NLRP3 PSEN1 PYCARD

TRIM44 Autophagy / lysosome / clearance 4 2 docs

Matched on TRIM44

Often named withACOX1 AKT1 (Akt)ATF4 BCL2 (Bcl-2)BECN1 CGAS

ACE2 Vascular / BBB 3 2 docs

Matched on ACE2

Often named withIL6 TNF APOE APP ATF4 AXL

APLP2 Amyloid & Tau core 3 1 doc

Matched on APLP2

Often named withABI3 ADAM10 AKT1 (Akt)APBB1 APOE APP

ATAD1 (Thorase) Bioenergetic / mito / NAD 3 2 docs

Matched on ATAD1 Thorase

Often named withADAM10 APOC1 APOE APP CYCS (cytochrome c)HSD17B10

ATF3 Cell death & ER stress 3 3 docs

Matched on ATF3

Often named withAPOE ATF4 CHAC1 DDIT3 (CHOP)PARP1 TREM2

ATP8B4 GWAS / LOAD risk 3 2 docs

Matched on ATP8B4

Often named withABCA1 ABCA7 ACAT1 ACSL4 APOE APP

AVP (vasopressin) Neuromodulator / circadian / kynurenine 3 1 doc

Matched on AVP vasopressin

Often named withAANAT APOE ARNTL (BMAL1)CASP3 MTNR1A/B

B2M Microglia & innate immunity 3 2 docs

Matched on B2M microglobulin

Often named withAGER (RAGE)APP ABCB1 (P-gp)ABCG2 (BCRP)APOE AQP4

CANX (calnexin) Cell death & ER stress 3 3 docs

Matched on CANX calnexin

Often named withAPP PSEN1 SORL1 TARDBP (TDP-43)APOE C9ORF72

CD44 Microglia & innate immunity 3 2 docs

Matched on CD44

Often named withACAN (aggrecan)APOE BCAN (brevican)CSF1R HAPLN1 HAPLN4 (Bral2)

CHAC1 Oxidative stress & ferroptosis 3 3 docs

Matched on CHAC1

Often named withAPOE ATF3 ATF4 DDIT3 (CHOP)PARP1 TREM2

CTSS (cathepsin S) Autophagy / lysosome / clearance 3 1 doc

Matched on CTSS cathepsin S

Often named withACAN (aggrecan)ADAMTS1 ADAMTS4 ADAMTS5 BCAN (brevican)CASP1

CXCL1 Microglia & innate immunity 3 3 docs

Matched on CXCL1

Often named withCD38 TP53 (p53)BCL2 (Bcl-2)BCL2L1 (Bcl-xL)CCL2 (MCP-1)CDKN1A (p21)

CXCR4 Microglia & innate immunity 3 2 docs

Matched on CXCR4

Often named withIL6 TLR4 TNF ABCB1 (P-gp)ACE2 AKT1 (Akt)

EXT1 Reelin, synapse & ECM–PNN 3 2 docs

Matched on EXT1

Often named withHS3ST2 LRP1 NDST1 PRNP ACAN (aggrecan)ADAMTS2

FUNDC1 Bioenergetic / mito / NAD 3 3 docs

Matched on FUNDC1

Often named withAPP MTOR OPTN PINK1 PRKAA (AMPK)PRKN

GLUL (glutamine synthetase) Astrocyte & glial markers 3 3 docs

Matched on GLUL glutamine synthetase

Often named withCD38 NLRP3 ACAN (aggrecan)APOE BCL2 (Bcl-2)BCL2L1 (Bcl-xL)

HLA-DRB1 GWAS / LOAD risk 3 2 docs

Matched on HLA-DRB1 HLA-DRB5 HLA-DR

Often named withABI3 ACAN (aggrecan)AIF1 (Iba1)APOE C1QA C3

HMGB1 Microglia & innate immunity 3 3 docs

Matched on HMGB1

Often named withAPOE C1QA C3 CDK5 GFAP GSK3B

HSPA5 (BiP/GRP78) Cell death & ER stress 3 1 doc

Matched on HSPA5 BiP GRP78

Often named withACE2 AXL CCR5 CD4 CXCR4 HTR2A

ITGAM Microglia & innate immunity 3 2 docs

Matched on ITGAM

Often named withABCA1 ABCA7 ABI3 ACAN (aggrecan)ACSL4 ADAMTS4

MAG Myelin & axon inhibition 3 2 docs

Matched on myelin[- ]associated glycoprotein

Often named withABCA7 APOE APP BACE1 C1QA CD33

MIF Microglia & innate immunity 3 3 docs

Matched on MIF macrophage migration inhibitory factor

Often named withCD74

MTNR1A/B Neuromodulator / circadian / kynurenine 3 1 doc

Matched on MTNR1A MTNR1B melatonin receptor

Often named withAANAT APOE ARNTL (BMAL1)AVP (vasopressin)CASP3

NOD2 Microglia & innate immunity 3 3 docs

Matched on NOD2

Often named withAKT1 (Akt)APP MTOR PSEN1 TLR4 TNF

NPC1 Autophagy / lysosome / clearance 3 2 docs

Matched on NPC1

Often named withAPOE APP BACE1 CTSD MAP1LC3B (LC3)PRKACA (PKA)

NRF1 (nuclear respiratory factor 1) Bioenergetic / mito / NAD 3 2 docs

Matched on NRF1

Often named withAPOE APP C1QA C3 C4 (complement)CR3

OMA1 Bioenergetic / mito / NAD 3 2 docs

Matched on OMA1

Often named withADAM10 APOC1 APOE APP ATAD1 (Thorase)CYCS (cytochrome c)

OXR1 Oxidative stress & ferroptosis 3 2 docs

Matched on OXR1

Often named withAPP ATP13A2 (PARK9)EPG5 FYN GBA GRN (progranulin)

P2RY13 Microglia & innate immunity 3 2 docs

Matched on P2RY13 P2Y13

Often named withACAN (aggrecan)APP BCAN (brevican)C1QA CD33 CX3CR1

PPP2R2A (B55α) Kinase & growth-factor signalling 3 3 docs

Matched on PPP2R2A B55

Often named withAKT1 (Akt)APOE APP FYN GSK3B PP2A

PPP5C (PP5) Kinase & growth-factor signalling 3 3 docs

Matched on PPP5C PP5

Often named withAPOE APP PP2A PPP1CA (PP1)MAOA/MAOB NLRP3

RCAN1 Down-syndrome chr21 3 1 doc

Matched on RCAN1 DSCR1

Often named withACAN (aggrecan)ADAMTS1 ADAMTS4 ADAMTS5 AGER (RAGE)APOE

SLC11A2 (DMT1) Oxidative stress & ferroptosis 3 2 docs

Matched on SLC11A2 DMT1

Often named withAIFM2 (FSP1)ALOX15 APOE FTH1/FTL (ferritin)GPX1 GPX4

SMCR8 Autophagy / lysosome / clearance 3 2 docs

Matched on SMCR8

Often named withAPOE APP C9ORF72 CTSB CTSD FUS

SOX2 Epigenetic & senescence 3 2 docs

Matched on SOX2

Often named withAPOE APP BDNF DCX (doublecortin)PVALB (parvalbumin)ACAN (aggrecan)

SREBF2 (SREBP-2) Lipid, sterol & membrane 3 2 docs

Matched on SREBF2 SREBP-?2

Often named withAKT1 (Akt)APOE APP MAPK14 (p38)MMP9 MTOR

TPH1 Neuromodulator / circadian / kynurenine 3 3 docs

Matched on TPH1

Often named withAPOE GRIN2B IDO1 IDO2 KMO TARDBP (TDP-43)

WDR41 Autophagy / lysosome / clearance 3 3 docs

Matched on WDR41

Often named withAPOE APP C9ORF72 CTSD FUS GBA

ADRA2A Neuromodulator / circadian / kynurenine 2 2 docs

Matched on ADRA2A alpha-?2[- ]adrenergic

Often named withABCA1 ABCA7 ABI3 ACAN (aggrecan)ACSL4 ADAMTS4

AIM2 Microglia & innate immunity 2 2 docs

Matched on AIM2

Often named withCD36 NFKB1 (NF-κB)NLRP3 PYCARD TLR4 TREM2

ATF6 Cell death & ER stress 2 2 docs

Matched on ATF6

Often named withAPP CASP3 PSEN1 ABCB1 (P-gp)AKT1 (Akt)APOE

ATG16L1 Autophagy / lysosome / clearance 2 2 docs

Matched on ATG16L1

Often named withCGAS DNM1L MTOR PINK1 PRKAA (AMPK)PRKN

ATG9A Autophagy / lysosome / clearance 2 2 docs

Matched on ATG9A?

Often named withAPP HTT (huntingtin)MAP1LC3B (LC3)MTOR PRKN PSEN1

BCL2L1 (Bcl-xL) Cell death & ER stress 2 2 docs

Matched on BCL2L1 Bcl-?xL

Often named withBCL2 (Bcl-2)CCL2 (MCP-1)CD38 CDKN1A (p21)CDKN2A (p16)CXCL1

BHMT Trophic / exercise / resilience 2 1 doc

Matched on BHMT

Often named withACHE ACSL1 APOE CHAT (ChAT)FLVCR2 MFSD2A

CASP9 Cell death & ER stress 2 2 docs

Matched on CASP9 caspase-?9

Often named withAPP BIN1 C1QA C3 CASP1 CASP8

CCR2 Microglia & innate immunity 2 2 docs

Matched on CCR2

Often named withTREM2 ACAN (aggrecan)ADAMTS4 AKT1 (Akt)APP ATG5

CDKN2D (p19INK4d) Epigenetic & senescence 2 1 doc

Matched on CDKN2D p19INK4d

Often named withACAN (aggrecan)APOE BCAN (brevican)BCL2 (Bcl-2)BCL2L1 (Bcl-xL)C1QA

CST3 (cystatin C) Amyloid & Tau core 2 2 docs

Matched on CST3 cystatin C

Often named withAPOE APP CD14 NLRP3 PSEN1 CAMP (LL-37)

CTSL (cathepsin L) Autophagy / lysosome / clearance 2 2 docs

Matched on CTSL cathepsin L

Often named withACAN (aggrecan)APOE APP BCAN (brevican)HAPLN1 HAPLN4 (Bral2)

CYP46A1 Lipid, sterol & membrane 2 2 docs

Matched on CYP46A1 24S-?hydroxylase

Often named withAPOE APP BACE1 NLRP3 V-ATPase (ATP6V)ABCA1

FOXO3 Trophic / exercise / resilience 2 2 docs

Matched on FOXO3

Often named withAKT1 (Akt)APP ATG5 ATG7 BCL2 (Bcl-2)CASP1

GCLM Oxidative stress & ferroptosis 2 1 doc

Matched on GCLM

Often named withACSL4 AIFM2 (FSP1)AIM2 ALOX15 ALOX5 APOE

GHRL (ghrelin) Neuromodulator / circadian / kynurenine 2 1 doc

Matched on GHRL ghrelin

Often named withCAMP (LL-37)CHAT (ChAT)CHRNA7 LEP (leptin)NFKB1 (NF-κB)PARP1

HMGCR Lipid, sterol & membrane 2 2 docs

Matched on HMGCR HMG-?CoA reductase

Often named withAPOE APP BACE1 BCL2 (Bcl-2)C1QA CLU

IFITM3 Microglia & innate immunity 2 1 doc

Matched on IFITM3

Often named withACOX1 AKT1 (Akt)ATF4 ATG16L1 BCL2 (Bcl-2)BECN1

KYNU Neuromodulator / circadian / kynurenine 2 1 doc

Matched on KYNU

Often named withABCA1 ABCA7 ABI3 ACAN (aggrecan)ACSL4 ADAMTS4

LAMP2 Autophagy / lysosome / clearance 2 2 docs

Matched on LAMP-?2

Often named withAPP BACE1 HSPA1A (Hsp70)MAP1LC3B (LC3)PINK1 PRKN

LRP2 (megalin) Vascular / BBB 2 1 doc

Matched on LRP2 megalin

Often named withAPOE CLDN5 CLU FOXP3 LRP1 NEFL (NfL)

NR1H3 (LXRα) Lipid, sterol & membrane 2 2 docs

Matched on NR1H3 LXR

Often named withACAN (aggrecan)APOE C1QA CX3CR1 GSK3B HTT (huntingtin)

OMG (OMgp) Myelin & axon inhibition 2 1 doc

Matched on OMgp

Often named withAGER (RAGE)APP B2M C1QA C3 C4 (complement)

RIN3 GWAS / LOAD risk 2 2 docs

Matched on RIN3

Often named withAPOE APP BACE1 BIN1 CD2AP PICALM

RTN4 (Nogo-A) Myelin & axon inhibition 2 1 doc

Matched on RTN4 Nogo-?A Nogo(?! ?receptor)

Often named withAGER (RAGE)APP B2M C1QA C3 C4 (complement)

SMAD4 Kinase & growth-factor signalling 2 2 docs

Matched on SMAD4

Often named withAPP CX3CL1 (fractalkine)CX3CR1 P2RY12 PSEN1 RELN

WWTR1 (TAZ) Kinase & growth-factor signalling 2 1 doc

Matched on WWTR1 TAZ

Often named withAPOE APP CD14 CGAS CST3 (cystatin C)EP300 (p300)

YAP1 Kinase & growth-factor signalling 2 1 doc

Matched on YAP1 YAP

Often named withAPOE APP CD14 CGAS CST3 (cystatin C)EP300 (p300)

ATG13 Autophagy / lysosome / clearance 1 1 doc

Matched on ATG13

Often named withAKT1 (Akt)APP AQP4 ATF6 ATG5 ATG7

C3AR1 Microglia & innate immunity 1 1 doc

Matched on C3aR C3AR1

Often named withACAN (aggrecan)ADRB (β-AR)APP BCAN (brevican)C1QA C5AR1

CAST (calpastatin) Reelin, synapse & ECM–PNN 1 1 doc

Matched on calpastatin

Often named withABCA7 APOE APP APPL1 ATG7 BACE1

EGFR Kinase & growth-factor signalling 1 1 doc

Matched on EGFR

Often named withAANAT ABCB1 (P-gp)ACAN (aggrecan)ACHE ADAMTS4 AKT1 (Akt)

ERN1 (IRE1) Cell death & ER stress 1 1 doc

Matched on ERN1 IRE1

Often named withAKT1 (Akt)APP AQP4 ATF6 ATG13 ATG5

LCMT1 Kinase & growth-factor signalling 1 1 doc

Matched on LCMT1

Often named withAPOE APP CD14 CGAS CST3 (cystatin C)EP300 (p300)

MTR (methionine synthase) Trophic / exercise / resilience 1 1 doc

Matched on methionine synthase

Often named withACHE ACSL1 APOE BHMT CHAT (ChAT)FLVCR2

NMNAT1 Bioenergetic / mito / NAD 1 1 doc

Matched on NMNAT1

Often named withABCB1 (P-gp)ACHE APOE ATF4 CD38 CHAT (ChAT)

NQO1 Oxidative stress & ferroptosis 1 1 doc

Matched on NQO1

Often named withAANAT ABCB1 (P-gp)ACAN (aggrecan)ACHE ADAMTS4 AKT1 (Akt)

NR3C1 (GR) Epigenetic & senescence 1 1 doc

Matched on NR3C1 glucocorticoid receptor

Often named withABCB1 (P-gp)APOE APP ATP13A2 (PARK9)BACE1 BCL2 (Bcl-2)

PCSK9 Lipid, sterol & membrane 1 1 doc

Matched on PCSK9

Often named withAPP ATP synthase (ATP5x)CD38 CXCL1 GPX4 IDO1

PLA2G4A (cPLA2) Microglia & innate immunity 1 1 doc

Matched on PLA2G4A cPLA2

Often named withABCA7 APOE APP ASAH1 (acid ceramidase)BACE1 BAX

RB1CC1 (FIP200) Autophagy / lysosome / clearance 1 1 doc

Matched on RB1CC1 FIP200

Often named withAKT1 (Akt)APP AQP4 ATF6 ATG13 ATG5

SERPINA3 Amyloid & Tau core 1 1 doc

Matched on SERPINA3 antichymotrypsin

Often named withABI3 APOE APP C3 CLU DLX1

SERPINE1 (PAI-1) Vascular / BBB 1 1 doc

Matched on SERPINE1 PAI-?1

Often named withACAT1 AKT1 (Akt)APOE APP BDNF CAMK2A (CaMKII)

SHANK3 Reelin, synapse & ECM–PNN 1 1 doc

Matched on SHANK3

Often named withABCA1 ABCA7 ABI3 ACAN (aggrecan)ACSL4 ADAMTS4

SIRT2 Bioenergetic / mito / NAD 1 1 doc

Matched on SIRT2

Often named withABCA1 ABCA7 ABI3 ACAN (aggrecan)ACSL4 ADAMTS4

SLC6A2 (NET) Neuromodulator / circadian / kynurenine 1 1 doc

Matched on SLC6A2 norepinephrine transporter

Often named withACAN (aggrecan)AKT1 (Akt)APOE APP BCAN (brevican)DAB1

SPOCK3 (testican-3) Reelin, synapse & ECM–PNN 1 1 doc

Matched on SPOCK3 testican-?3

Often named withABI3 APOE APP C3 CLU DLX1

SSH2 Reelin, synapse & ECM–PNN 1 1 doc

Matched on SSH2

Often named withACAN (aggrecan)APOE APP ARHGEF15 (Ephexin5)BCAN (brevican)C1QA

TLR9 Microglia & innate immunity 1 1 doc

Matched on TLR9

Often named withACAN (aggrecan)AKT1 (Akt)APOE APP ATP synthase (ATP5x)ATP2A2 (SERCA2)

Gene Index

Method

Discussion